Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.80 |
| ▸ | GALR3 | O60755 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265939 | 0.90 | SMN1; SMN2 (0.72) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL10409575 | 0.90 | SMN1; SMN2 (0.65) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| Carboxyamidotriazole SCHEMBL18866 | 0.89 | SMN1; SMN2 (1.00) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL7264556 | 0.89 | SMN1; SMN2 (0.78) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL7271947 | 0.89 | SMN1; SMN2 (0.74) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| Carboxyamidotriazole SCHEMBL8467240 | 0.88 | SMN1; SMN2 (0.98) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL7264526 | 0.87 | SMN1; SMN2 (0.80) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL7270852 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL17507850 | 0.85 | SMN1; SMN2 (0.88) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 | |
| SCHEMBL7264241 | 0.84 | SMN1; SMN2 (0.86) | SMN1; SMN2GALR3CYP3A4CYP2C9NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |