Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | CPA3 | P15088 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384110 | 1.00 | CYP1A2 (0.52) | CYP1A2ADAMTS5NPC1RAB9AALPI | |
| SCHEMBL19729280 | 0.87 | MEN1 (0.49) | CYP1A2NPC1RAB9AALPIPKM | |
| SCHEMBL19542979 | 0.86 | NPC1 (0.46) | CYP1A2NPC1RAB9AALPIPKM | |
| SCHEMBL22384007 | 0.86 | SLC7A5 (0.51) | PTGS1SLC7A5CPA1FOLH1 | |
| SCHEMBL22872362 | 0.84 | ADAMTS5 (0.51) | CYP1A2ADAMTS5NPC1RAB9AALPI | |
| SCHEMBL13957690 | 0.84 | ADAMTS5 (0.51) | CYP1A2ADAMTS5NPC1RAB9AALPI | |
| SCHEMBL2780442 | 0.82 | ALPI (0.50) | CYP1A2ADAMTS5NPC1RAB9AALPI | |
| SCHEMBL121728 | 0.81 | MAPT (0.61) | CYP1A2ADAMTS5ALPIPKMPTGS1 | |
| SCHEMBL121727 | 0.81 | MAPT (0.61) | CYP1A2ADAMTS5ALPIPKMPTGS1 | |
| SCHEMBL1573822 | 0.81 | CYP1A2 (0.55) | CYP1A2ADAMTS5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963530-A | Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0283970-A2 | New peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |