Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.54 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869190 | 0.89 | ADORA3 (0.43) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL7268196 | 0.86 | ADORA3 (0.52) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL7275805 | 0.84 | TBXA2R (0.57) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL11520735 | 0.83 | CACNA1C (0.54) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL9833019 | 0.81 | CACNA1C (0.64) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL10615427 | 0.80 | ADORA3 (0.52) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL7467067 | 0.80 | CACNA1C (0.51) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL9513012 | 0.80 | CACNA1C (0.53) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL7275404 | 0.80 | TBXA2R (0.52) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C | |
| SCHEMBL7436084 | 0.79 | TBXA2R (0.51) | TBXA2RADRA1ASLC6A3ADORA3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292981-B1 | 2-SELENOMETHYL-1, 4-DIHYDROPYRIDINES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-04-17 | — | — | EP | claimed |
| EP-0292981-A2 | 2-Selenomethyl-1, 4-dihydropyridines, a process for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-11-30 | — | — | EP | claimed |
| EP-0292981-B1 | 2-SELENOMETHYL-1, 4-DIHYDROPYRIDINES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-04-17 | — | — | EP | disclosed |