Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 15/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273069 | 0.88 | CACNA1F (0.43) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7267128 | 0.88 | CACNA1B (0.43) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7275680 | 0.84 | CACNA1F (0.57) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7272004 | 0.83 | CACNA1B (0.43) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7265905 | 0.83 | CACNA1F (0.50) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7272283 | 0.82 | ADORA3 (0.57) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7272395 | 0.82 | CACNA1F (0.50) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7273557 | 0.81 | CACNA1B (0.42) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7275995 | 0.81 | KDM4E (0.45) | CACNA1BCACNA1C | |
| SCHEMBL7267803 | 0.81 | CACNA1B (0.41) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |