SCHEMBL726787

SCHEMBL726787

Cc1nc2c3ccsc3c3sccc3c2nc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.40
▸ TSHR P16473 1/20 0.40
▸ DYRK1A Q13627 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.35
▸ MAPK1 P28482 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CHEK1 O14757 1/20 0.32
▸ AURKA O14965 1/20 0.32
▸ DAPK3 O43293 1/20 0.32
▸ JAK2 O60674 1/20 0.32
▸ MAP4K4 O95819 1/20 0.32
▸ ABL1 P00519 1/20 0.32
▸ NTRK1 P04629 1/20 0.32
▸ LCK P06239 1/20 0.32
▸ FYN P06241 1/20 0.32
▸ CSF1R P07333 1/20 0.32
▸ RET P07949 1/20 0.32
▸ IGF1R P08069 1/20 0.32
▸ MET P08581 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954487 0.76 MAPT (0.42) MAPTKDM4EHSD17B10ALDH1A1KMT2A
SCHEMBL13641584 0.74 KDM4E (0.33) MAPTTSHRDYRK1AKDM4EPIM1
SCHEMBL19104641 0.72 MAPT (0.35) MAPTTSHR
SCHEMBL23144944 0.71 KDM4E (0.41) MAPTTSHRDYRK1AKDM4ECHEK1
SCHEMBL10028817 0.71 KDM4E (0.49) MAPTTSHRDYRK1AKDM4EHSD17B10
SCHEMBL24284162 0.71 MAPT (0.36) MAPTTSHRDYRK1AKDM4EMAPK1
SCHEMBL13641594 0.71 CSNK2A1 (0.36) MAPTTSHRKDM4EPDGFRBPIM1
SCHEMBL23145016 0.70 KDM4E (0.36) MAPTTSHRDYRK1AKDM4E
SCHEMBL11316439 0.70 DYRK1A (0.34) MAPTTSHRDYRK1AKDM4EMAPK1
SCHEMBL15424578 0.70 MAPT (0.43) MAPTTSHRKDM4EALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184390-B2 Polymers with tunable band gaps for photonic and electronic applications THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2015-11-10 — — US disclosed
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2013-04-18 — — US disclosed
WO-2011156478-A2 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-12-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS GJB2, PARG, PARN MAPT 2075/4885TSHR 4836/4885DYRK1A 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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