Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103549 | 0.87 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL8543900 | 0.84 | TAAR1 (0.47) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL11568003 | 0.82 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL8051573 | 0.79 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL1509682 | 0.79 | TAAR1 (0.67) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL4018722 | 0.79 | TAAR1 (0.67) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL6112047 | 0.79 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL2775376 | 0.79 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| Hydrochloric Acid SCHEMBL29751822 | 0.77 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL2366649 | 0.76 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CTAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8646616-B2 | Composite membrane with coating comprising polyalkylene oxide and imidazol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-11 | — | — | US | disclosed |
| WO-2011149572-A1 | POLYAMIDE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110284454-A1 | COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-24 | — | — | US | disclosed |
| US-4507311-A | Imidazo[1,2-c][1,3]benzodiazepines | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4460587-A | ANTIPSYCHOTIC AGENTS, ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4460508-A | 5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4459232-A | NEUROLEPTIC, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0081461-A2 | Imidazobenzodiazepines, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-06-15 | — | — | EP | disclosed |
| US-4006243-A | FUNGICIDE, BACTERICIDE, YEAST | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |