SCHEMBL7268282

SCHEMBL7268282

O=P(Cl)(OCC1c2ccccc2-c2ccccc21)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
HTR2A P28223 1/20 0.44
KMT2A Q03164 2/20 0.41
FABP5 Q01469 3/20 0.40
FABP7 O15540 2/20 0.40
EPHX2 P34913 1/20 0.38
POLB P06746 1/20 0.34
MDM4 O15151 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865065 1.00 CA1 (0.50) CA1CA2HTR2AKMT2AFABP5
SCHEMBL29221536 0.86 CA1 (0.47) CA1CA2HTR2AKMT2AFABP5
SCHEMBL7269639 0.85 CA1 (0.58) CA1CA2HTR2AKMT2AFABP5
SCHEMBL7268207 0.81 CA1 (0.50) CA1CA2HTR2AKMT2AFABP5
SCHEMBL87486 0.81 CA1 (0.50) CA1CA2HTR2AKMT2AFABP5
SCHEMBL29221537 0.80 CA1 (0.45) CA1CA2HTR2AKMT2AFABP5
Tetramethylammonium Ion SCHEMBL7263735 0.76 CA1 (0.45) CA1CA2HTR2AKMT2AFABP5
SCHEMBL18736421 0.76 CA1 (0.45) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28455214 0.76 CA1 (0.49) CA1CA2HTR2AKMT2AFABP5
SCHEMBL4992955 0.74 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs DRUG INNOVATION & DESIGN, INC. 2003-07-24 US disclosed
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP disclosed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs PAICS, ABCB1, ABCG2 CA1 1757/4885CA2 1014/4885HTR2A 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.