Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.42 |
| ▸ | FABP7 | O15540 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730698 | 0.81 | CA1 (0.57) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL20362789 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL31370732 | 0.77 | HTR2A (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL15372784 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL158137 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL31501939 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL28050 | 0.77 | HTR2A (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL8131 | 0.77 | CA1 (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL456018 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL13044481 | 0.75 | KMT2A (0.52) | CA1CA2HTR2AKMT2AFABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115932123-A | Method for detecting trace L-proline in L-prolinol | 华南理工大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111995513-B | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114778743-A | Method for detecting trace chiral isomer D-proline in L-proline | 常州制药厂有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112300058-A | Method for extracting 1-deoxynojirimycin from fresh mulberry leaves | 中国热带农业科学院热带作物品种资源研究所 | 2021-02-02 | — | — | CN | disclosed |
| CN-112043839-A | Radioisotope-labeled polypeptide imaging agent targeting transferrin receptor and application thereof | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2020-12-08 | — | — | CN | disclosed |
| CN-111995513-A | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110632187-A | Method for determining D-buckwheat alkali in buckwheat by using pre-column derivatization high performance liquid chromatography-fluorescence detector | 西北农林科技大学 | 2019-12-31 | — | — | CN | disclosed |
| CN-110632187-A | Method for determining D-buckwheat alkali in buckwheat by using pre-column derivatization high performance liquid chromatography-fluorescence detector | 西北农林科技大学 | 2019-12-31 | — | — | CN | disclosed |
| US-20140050778-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012092367-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2012-07-05 | — | — | WO | disclosed |
| US-7153869-B2 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J | 2006-12-26 | — | — | US | disclosed |
| US-20060247274-A1 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J | 2006-11-02 | — | — | US | disclosed |
| US-20040248815-A1 | Substituted amino acids as erythropoietin mimetics | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1073623-A4 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | ORTHO MCNEIL PHARM INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6750369-B2 | USEFUL IN TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH ERYTHROPOIETIN RECEPTOR | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2004-06-15 | — | — | US | disclosed |
| US-20020016350-A1 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J (US) | 2002-02-07 | — | — | US | disclosed |
| US-6310078-B1 | MODULATING ERYTHROPOIETIN RECEPTOR, TREATING DISEASE OR CONDITION MEDIATED BY SAID RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-30 | — | — | US | disclosed |
| US-6306911-B1 | ENZYME INHIBITORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-1073623-A1 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054279-A1 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247274-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, EDNRB | CA1 4313/4885CA2 4058/4885HTR2A 2795/4885 |
| US-20020016350-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, FLT1 | CA1 4023/4885CA2 4179/4885HTR2A 2999/4885 |
| US-20140050778-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | NSUN3, NSUN2, HNRNPF | CA1 4315/4885CA2 4776/4885HTR2A 3442/4885 |
| US-20040248815-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, FLT1 | CA1 4023/4885CA2 4179/4885HTR2A 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.