Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051966 | 0.82 | ACE (0.35) | PREPACETSHRDPP4HTT | |
| SCHEMBL2525637 | 0.80 | ACE (0.34) | ACEPOLBKDM4EDPP4ALDH1A1 | |
| SCHEMBL9878022 | 0.79 | ATM (0.39) | PREPSMN1; SMN2 | |
| SCHEMBL6052020 | 0.79 | ACE (0.33) | ACEDPP4 | |
| Telmesteine SCHEMBL637246 | 0.77 | ACE (0.53) | PREPACEGAATSHR | |
| Telmesteine SCHEMBL1425417 | 0.77 | ACE (0.53) | PREPACEGAATSHR | |
| SCHEMBL9362245 | 0.75 | ACE (0.32) | ACE | |
| SCHEMBL10783221 | 0.73 | DPP4 (0.42) | PREPACEDPP4 | |
| SCHEMBL11384419 | 0.73 | ACE (0.63) | ACEKDM4E | |
| SCHEMBL10926791 | 0.73 | ACE (0.63) | ACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348541-B1 | N-CARBETHOXY-4-THIAZOLIDINE-CARBOXYLIC ACID, PROCESS FOR ITS PREPARATION AND ITS USE AS MEDICAMENT | YASON S.r.l (IT) | 1992-04-01 | — | — | EP | claimed |