SCHEMBL7268582

SCHEMBL7268582

CCCC[C@H](NC(=O)[C@H](Cc1cccc2cccnc12)CS(=O)(=O)CC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CN1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7275465 0.90 REN (0.52) REN
SCHEMBL7267995 0.90 REN (0.52) REN
SCHEMBL7268447 0.88 REN (0.54) REN
SCHEMBL7267836 0.87 REN (0.48) REN
SCHEMBL7267436 0.86 REN (0.52) REN
SCHEMBL7268089 0.86 REN (0.62) REN
SCHEMBL7273905 0.86 REN (0.49) REN
SCHEMBL9574611 0.84 REN (0.52) REN
SCHEMBL7286975 0.84 REN (0.52) REN
SCHEMBL7266771 0.84 REN (0.54) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309766-B1 N-acylamino acid derivatives and their use BANYU PHARMA CO LTD (JP) 1998-04-15 — — EP claimed
EP-0309766-A2 N-acylamino acid derivatives and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-05 — — EP claimed
US-5481036-A RENIN INHIBITORS, HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-01-02 — — US disclosed
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