Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270748 | 0.92 | HTR3A (0.53) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7275994 | 0.91 | HTR3A (0.51) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7270685 | 0.89 | HTR3A (0.49) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7270299 | 0.88 | HTR3A (0.49) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7270305 | 0.87 | HTR3A (0.47) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7270766 | 0.87 | HTR3A (0.49) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7276056 | 0.87 | HTR3A (0.47) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Fumaric Acid SCHEMBL7268689 | 0.79 | HTR3A (0.60) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Fumaric Acid SCHEMBL7268699 | 0.79 | HTR3A (0.60) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL9485018 | 0.79 | HTR3A (0.57) | HTR3AKCNH2HTR2ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |