Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268391 | 1.00 | PREP (1.00) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL6696041 | 0.91 | PREP (0.83) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL4977449 | 0.91 | PREP (0.83) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL7269927 | 0.89 | PREP (0.81) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL7268319 | 0.89 | PREP (0.81) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL9872924 | 0.86 | PREP (0.76) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL9872921 | 0.86 | PREP (0.76) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL9872918 | 0.86 | PREP (0.76) | PREPNPSR1ALDH1A1CTRB1KMT2A | |
| SCHEMBL9873047 | 0.86 | PREP (0.75) | PREPNPSR1CTRB1KMT2ATSHR | |
| SCHEMBL9873052 | 0.86 | PREP (0.75) | PREPNPSR1CTRB1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158970-A | Prolylendopeplidase inhibitors; antiamnesia | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | disclosed |