⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293036 | 0.77 | — | — | |
| SCHEMBL3542282 | 0.69 | — | — | |
| SCHEMBL9596129 | 0.65 | — | — | |
| SCHEMBL29017880 | 0.64 | — | — | |
| SCHEMBL6420085 | 0.64 | — | — | |
| SCHEMBL16238310 | 0.64 | — | — | |
| SCHEMBL1866399 | 0.64 | — | — | |
| SCHEMBL17185567 | 0.64 | — | — | |
| SCHEMBL5583489 | 0.62 | — | — | |
| SCHEMBL3969262 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054491-B2 | Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators | UWM RESEARCH FOUNDATION, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-20230103216-A1 | GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA | UWM RESEARCH FOUNDATION, INC. | 2023-03-30 | — | — | US | disclosed |
| US-11447495-B2 | Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators | UWM RESEARCH FOUNDATION, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-109790170-B | GABA (A) receptor modulators and methods of controlling airway hyperresponsiveness and inflammation in asthma | UWM研究基金会有限公司 | 2022-08-02 | — | — | CN | disclosed |
| EP-0484204-A1 | 7-Cycloalkylimidazodiazepines and their salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1992-05-06 | — | — | EP | disclosed |
| EP-0395527-A1 | Imidazobenzodiazepines and their salts, process for preparation, use as medicaments, and compositions containing these compounds | ROUSSEL-UCLAF (FR) | 1990-10-31 | — | — | EP | disclosed |