SCHEMBL7269574

SCHEMBL7269574

C=C(C)C(=O)OCCOC(=O)CCc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.46
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 4/20 0.39
ALOX5 P09917 1/20 0.37
ALDH1A1 P00352 7/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 4/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 3/20 0.35
YWHAG P61981 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 1/20 0.35
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
P2RY12 Q9H244 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20598749 0.94 APP (0.45) APPNPC1RAB9ALMNATDP1
SCHEMBL93485 0.91 NPC1 (0.47) APPNPC1RAB9ALMNATDP1
SCHEMBL29358846 0.91 NPC1 (0.47) APPNPC1RAB9ALMNATDP1
SCHEMBL29382102 0.89 NPC1 (0.45) APPNPC1RAB9ALMNATDP1
SCHEMBL373620 0.89 NPC1 (0.45) APPNPC1RAB9ALMNATDP1
SCHEMBL25412291 0.88 LMNA (0.44) NPC1RAB9ALMNATDP1ALOX5
SCHEMBL8823408 0.88 LMNA (0.43) APPNPC1RAB9ALMNAALDH1A1
SCHEMBL692084 0.88 LMNA (0.43) NPC1RAB9ALMNATDP1ALOX5
SCHEMBL29384533 0.88 LMNA (0.43) NPC1RAB9ALMNATDP1ALOX5
SCHEMBL28006703 0.88 LMNA (0.43) NPC1RAB9ALMNATDP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160054840-A1 TOUCH SENSOR WITH FRONT PANEL ASAHI GLASS COMPANY, LIMITED (JP) 2016-02-25 US disclosed
US-20130164543-A1 FRONT PANEL FOR TOUCH SENSOR ASAHI GLASS COMPANY, LIMITED (JP) 2013-06-27 US disclosed
EP-0899091-B1 Transparent coated molded product and method for producing the same ASAHI GLASS CO LTD (JP) 2003-10-29 EP disclosed
US-6383641-B1 CURED INTERIOR LAYER FROM POLYFUNCTIONAL COMPOUND; EXTERIOR SILICA COATING CURED FROM POLYSILAZANE; WEAR RESISTANCE, WEATHERPROOF ASAHI GLASS COMPANY LTD. (JP) 2002-05-07 US disclosed
EP-0899091-A2 Transparent coated molded product and method for producing the same Asahi Glass Company Ltd. (JP) 1999-03-03 EP disclosed