SCHEMBL7269679

SCHEMBL7269679

CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)C(CC(=O)N1CCOCC1)Cc1ccc(OC)cc1)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269685 1.00 REN (0.65) REN
SCHEMBL7279152 1.00 REN (0.65) REN
SCHEMBL7269504 0.94 REN (0.66) REN
SCHEMBL7269503 0.94 REN (0.66) REN
SCHEMBL7269576 0.94 REN (0.66) REN
SCHEMBL7269381 0.93 REN (0.75) REN
SCHEMBL7277408 0.93 REN (0.75) REN
SCHEMBL7269379 0.93 REN (0.75) REN
SCHEMBL7279339 0.92 REN (0.69) REN
SCHEMBL7270369 0.92 REN (0.69) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383635-B1 Peptides having renin inhibitory activity their preparation and use SANKYO CO (JP) 1995-07-12 — — EP claimed
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