Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.59 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262278 | 1.00 | KIF11 (0.59) | KIF11MIFKCNN4ADRB2HTR1A | |
| SCHEMBL7268298 | 0.95 | KIF11 (0.65) | KIF11MIFKCNN4ADRB2HTR1A | |
| SCHEMBL7263720 | 0.95 | KIF11 (0.65) | KIF11MIFKCNN4ADRB2HTR1A | |
| SCHEMBL7268289 | 0.94 | KIF11 (0.67) | KIF11MIFKCNN4SMN1; SMN2DUT | |
| SCHEMBL7263691 | 0.92 | KIF11 (0.53) | KIF11MIFKCNN4SMN1; SMN2DUT | |
| SCHEMBL18475596 | 0.87 | KIF11 (0.54) | KIF11MIFKCNN4SMN1; SMN2DRD2 | |
| SCHEMBL10071082 | 0.85 | KIF11 (0.56) | KIF11MIFKCNN4SMN1; SMN2DRD2 | |
| SCHEMBL7268287 | 0.84 | KIF11 (0.46) | KIF11MIFKCNN4SMN1; SMN2DUT | |
| SCHEMBL5973130 | 0.84 | KIF11 (0.51) | KIF11MIFKCNN4SMN1; SMN2DRD2 | |
| SCHEMBL7263696 | 0.81 | KIF11 (0.42) | KIF11MIFKCNN4SMN1; SMN2DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030138432-A1 | Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs | DRUG INNOVATION & DESIGN, INC. | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138432-A1 | Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs | PAICS, ABCB1, ABCG2 | KIF11 3005/4885MIF 488/4885KCNN4 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.