Sugi Predict

Sugi Predict / Compounds / SCHEMBL7269781

SCHEMBL7269781

SCHEMBL7269781

CCCCC(C)C(=O)NC(C)C

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.48
▸ FAAH O00519 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ CA1 P00915 4/20 0.47
▸ EPHX1 P07099 1/20 0.46
▸ DPP7 Q9UHL4 4/20 0.44
▸ DPP8 Q6V1X1 3/20 0.44
▸ SLC15A1 P46059 1/20 0.44
▸ CNR1 P21554 4/20 0.44
▸ CA2 P00918 2/20 0.44
▸ DPP4 P27487 2/20 0.42
▸ DPP9 Q86TI2 2/20 0.42
▸ CTSK P43235 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ FDPS P14324 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25761064 0.94 CA1 (0.55) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL9462411 0.86 MAPK1 (0.43) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL27459062 0.86 MAPK1 (0.43) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL12992885 0.85 CA1 (0.47) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL19522454 0.83 BLM (0.45) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL22304123 0.82 CNR1 (0.63) CA1DPP7DPP8SLC15A1CNR1
SCHEMBL11934340 0.81 MEN1 (0.47) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL9834060 0.81 MEN1 (0.47) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL10213719 0.81 TSHR (0.35) MEN1FAAHMAPK1KMT2ACA1
SCHEMBL23449935 0.80 CA1 (0.48) MAPK1CA1DPP7DPP8SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383635-B1 Peptides having renin inhibitory activity their preparation and use SANKYO CO (JP) 1995-07-12 — — EP claimed
EP-0383635-A2 Peptides having renin inhibitory activity their preparation and use Sankyo Company Limited (JP) 1990-08-22 — — EP claimed
US-9572823-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-21 — — US disclosed
US-9566290-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9566289-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9549938-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-01-24 — — US disclosed
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-07-21 — — US disclosed
US-20160184334-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-06-30 — — US disclosed
US-20160151399-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-06-02 — — US disclosed
US-20150119364-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2015-04-30 — — US disclosed
US-20130210770-A1 PHARMACEUTICAL FORMULATIONS ANACOR PHARMACEUTICALS, INC. (US) 2013-08-15 — — US disclosed
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-8115026-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2012-02-14 — — US disclosed
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-21 — — US disclosed
US-7767657-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2010-08-03 — — US disclosed
US-20070155699-A1 Boron-containing small molecules ANACOR PHARMACEUTICALS (US) 2007-07-05 — — US disclosed
EP-0383635-B1 Peptides having renin inhibitory activity their preparation and use SANKYO CO (JP) 1995-07-12 — — EP disclosed
US-5224987-A Aqueous carriers with colors and tertiary amide penetrants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-06 — — US disclosed
EP-0383635-A2 Peptides having renin inhibitory activity their preparation and use Sankyo Company Limited (JP) 1990-08-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20160151399-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20130210770-A1 PHARMACEUTICAL FORMULATIONS DPM1, POLR1C, ETF1 MEN1 1075/4885FAAH 3567/4885MAPK1 3510/4885
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20070155699-A1 Boron-containing small molecules ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20160184334-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885
US-20150119364-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 MEN1 522/4885FAAH 3642/4885MAPK1 1528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.