Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758086 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL414397 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL11048505 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL31261832 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL11216416 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL2241808 | 0.76 | APP (0.48) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL9626191 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL11573251 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL9547910 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GPABPC1 | |
| SCHEMBL25148807 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630597-B1 | Photochromic 6-aryl substituted 3H-naphtho(2, 1-b)pyran compounds, examples of which are naphthopyran compounds having a substituted aryl group at the number 6 carbon atom and certain substituents at the 3-position of the pyran ring | TRANSITIONS OPTICAL, INC. | 2003-10-07 | — | — | US | disclosed |
| EP-1042311-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO 2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031082-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-06-24 | — | — | WO | disclosed |