Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9484770 | 0.99 | HTR3A (0.64) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL7270543 | 0.85 | HTR3A (0.64) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL7269322 | 0.84 | HTR3A (0.72) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL7276068 | 0.84 | HTR3A (0.72) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL7269326 | 0.84 | HTR3A (0.72) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL7281271 | 0.84 | HTR3A (0.71) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9484941 | 0.84 | HTR3A (0.58) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL7269107 | 0.84 | HTR3A (0.71) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| SCHEMBL10476919 | 0.83 | HTR3A (0.67) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL7288488 | 0.83 | HTR3A (0.70) | HTR3AKCNH2CYP1A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | claimed |
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |