Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270109 | 0.81 | CYP2C19 (0.54) | POLBCYP3A4CYP2C19HDAC8TDP1 | |
| SCHEMBL18711805 | 0.80 | POLB (0.65) | POLBCYP3A4CYP2C19PREPHDAC8 | |
| SCHEMBL9596147 | 0.80 | POLB (0.65) | POLBCYP3A4CYP2C19HDAC8TDP1 | |
| SCHEMBL8538945 | 0.79 | CYP2C19 (0.52) | POLBCYP3A4CYP2C19HDAC8TDP1 | |
| SCHEMBL14183936 | 0.77 | HDAC8 (0.62) | POLBCYP3A4CYP2C19HDAC8PTPN1 | |
| SCHEMBL18711811 | 0.77 | POLB (0.61) | POLBCYP3A4CYP2C19HDAC8TDP1 | |
| SCHEMBL7270808 | 0.77 | CYP2C19 (0.50) | POLBCYP3A4CYP2C19HDAC8 | |
| SCHEMBL9595767 | 0.75 | POLB (0.48) | POLBCYP3A4CYP2C19HDAC8FNTA | |
| SCHEMBL9572243 | 0.74 | NPSR1 (0.64) | POLBCYP3A4CYP2C19HDAC8LMNA | |
| SCHEMBL9572242 | 0.74 | NPSR1 (0.64) | POLBCYP3A4CYP2C19HDAC8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |