Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249468 | 0.86 | MAP3K14 (0.35) | MAP3K14GLAMEN1APEX1KMT2A | |
| SCHEMBL8891060 | 0.82 | DPP4 (0.34) | GLA | |
| SCHEMBL9797984 | 0.80 | NPC1 (0.33) | CRBNDDB1 | |
| SCHEMBL9214203 | 0.80 | PTGS1 (0.32) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL20292600 | 0.79 | MAP3K14 (0.36) | MAP3K14GLATDP1CRBNDDB1 | |
| SCHEMBL8745670 | 0.78 | MAP3K14 (0.32) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL756451 | 0.77 | CRBN (0.38) | MAP3K14GLAMEN1APEX1KMT2A | |
| SCHEMBL978471 | 0.77 | — | — | |
| SCHEMBL612318 | 0.77 | — | — | |
| SCHEMBL7380755 | 0.77 | KMT2A (0.43) | KMT2ACRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545624-A | USEFUL IN TREATING BACTERIAL OR MYCOPLASMIC INFECTIONS | PFIZER INC. (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0295316-B1 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID CO (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0295316-A2 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |