Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385948 | 0.86 | CYP19A1 (0.41) | KMT2ARAB9ACREBBPBRD4DDB1 | |
| SCHEMBL7385463 | 0.84 | DDB1 (0.34) | KMT2ADDB1CRBNGPBAR1HSD17B10 | |
| SCHEMBL7378937 | 0.81 | KCNQ2 (0.40) | KMT2AHSD17B10TP53GAACYP1A2 | |
| SCHEMBL7379863 | 0.81 | MEN1 (0.44) | KMT2AGAAMAPK1 | |
| SCHEMBL7381326 | 0.81 | MEN1 (0.44) | KMT2AGAAMAPK1 | |
| SCHEMBL6667157 | 0.79 | HCAR2 (0.43) | RAB9ACREBBPBRD4DDB1CRBN | |
| SCHEMBL7383592 | 0.79 | CHRM2 (0.39) | KMT2ARAB9ADDB1CRBNCYP1A2 | |
| SCHEMBL7385425 | 0.79 | KCNQ2 (0.39) | KMT2ACREBBPBRD4CYP1A2TSHR | |
| SCHEMBL7270134 | 0.77 | MAP3K14 (0.33) | KMT2ADDB1CRBN | |
| SCHEMBL9249468 | 0.77 | MAP3K14 (0.35) | KMT2ADDB1CRBNGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |