Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285680 | 0.89 | HTR2C (0.45) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL6001297 | 0.81 | HTR2C (0.47) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL7264096 | 0.81 | HTR2C (0.47) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL14673362 | 0.73 | — | — | |
| SCHEMBL18760220 | 0.73 | — | — | |
| SCHEMBL2202910 | 0.71 | DDB1 (0.44) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL2202906 | 0.71 | DDB1 (0.44) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL30155273 | 0.70 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL19994437 | 0.69 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL8522162 | 0.69 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |