Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074155 | 0.91 | ALDH1A1 (0.49) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL2954111 | 0.83 | MAPT (0.62) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL7269722 | 0.82 | PARP1 (0.60) | GAAALDH1A1MAPTLMNARXFP1 | |
| SCHEMBL4293605 | 0.81 | ALDH1A1 (0.68) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL592296 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTPARP1POLBRAB9A | |
| SCHEMBL4288362 | 0.80 | ALDH1A1 (0.65) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL531798 | 0.79 | TSHR (0.74) | GAAALDH1A1MAPTLMNAPKM | |
| SCHEMBL19833756 | 0.79 | GAA (0.53) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL4654077 | 0.78 | GAA (0.76) | GAACASP3SENP7ALDH1A1MAPT | |
| SCHEMBL6752 | 0.78 | ALDH1A1 (0.63) | GAACASP3SENP7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |