Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922207 | 0.88 | OPRM1 (0.31) | — | |
| SCHEMBL11817414 | 0.82 | PARP1 (0.34) | — | |
| SCHEMBL5585759 | 0.79 | S1PR1 (0.32) | SIGMAR1EBPS1PR1S1PR3S1PR5 | |
| SCHEMBL10867277 | 0.79 | — | — | |
| SCHEMBL3298354 | 0.79 | — | — | |
| SCHEMBL9150873 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27461147 | 0.77 | — | — | |
| SCHEMBL5585723 | 0.76 | S1PR1 (0.30) | S1PR1S1PR3S1PR5 | |
| SCHEMBL11049865 | 0.74 | MEN1 (0.31) | S1PR1S1PR3S1PR5 | |
| SCHEMBL23251421 | 0.73 | S1PR1 (0.31) | SIGMAR1EBPS1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |