Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270335 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL5193497 | 0.77 | CYP3A4 (0.61) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL4099299 | 0.77 | CYP2C19 (0.47) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL4092212 | 0.77 | CYP2C19 (0.47) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL4092217 | 0.77 | CYP2C19 (0.47) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL6431176 | 0.76 | CYP3A4 (0.59) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL9068773 | 0.75 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4106419 | 0.75 | NOS1 (0.46) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL18272090 | 0.74 | CYP2D6 (0.61) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL1654642 | 0.73 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |