Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278134 | 0.86 | AKR1B1 (0.38) | CYP3A4DRD2MYCNR4A1AKR1C4 | |
| SCHEMBL7290561 | 0.76 | DYRK1A (0.37) | CYP3A4MYCNR4A1AKR1C4AKR1C3 | |
| SCHEMBL7274861 | 0.74 | DRD2 (0.51) | CYP3A4DRD2MYCNR4A1AKR1C4 | |
| Hydrochloric Acid SCHEMBL7270776 | 0.73 | DRD2 (0.50) | CYP3A4DRD2MYCNR4A1AKR1C4 | |
| SCHEMBL7276148 | 0.72 | CYP3A4 (0.37) | CYP3A4DRD2MYCNR4A1AKR1C4 | |
| SCHEMBL7282398 | 0.72 | HTR2A (0.36) | CYP3A4MYCNR4A1AKR1C4AKR1C3 | |
| SCHEMBL9485659 | 0.70 | MAPT (0.41) | MYCNR4A1KDM4ENOTUM | |
| SCHEMBL7287801 | 0.69 | HSD17B10 (0.46) | MYCNR4A1AKR1C4AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL7291096 | 0.69 | HSD17B10 (0.46) | MYCNR4A1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL18334430 | 0.68 | MAPT (0.37) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |