Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.57 |
| ▸ | NQO2 | P16083 | 10/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270914 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7270912 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8073051 | 0.90 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6401566 | 0.90 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7272279 | 0.86 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7272276 | 0.86 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL12307954 | 0.85 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7271026 | 0.84 | KMT2A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7271030 | 0.84 | KMT2A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7271031 | 0.84 | KMT2A (0.51) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420480-A | PARKINSONISM, DEPRESSION, HYPOTENSIVES | MERCK & CO., INC. (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0080115-A2 | Hexahydronaphth(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them | MERCK & CO. INC. (US) | 1983-06-01 | — | — | EP | disclosed |