Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905608 | 0.82 | CHRNB4 (0.47) | CHRNB4CHRNA3 | |
| SCHEMBL4816733 | 0.80 | CHRM1 (0.44) | CHRM1 | |
| SCHEMBL26731759 | 0.78 | CHRNB4 (0.56) | CHRNB4CHRNA3HSD17B10CHRM1 | |
| SCHEMBL25981119 | 0.77 | PER2 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL1797592 | 0.76 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL1797593 | 0.76 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL6819282 | 0.76 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL16902666 | 0.75 | HRH3 (0.50) | ALDH1A1 | |
| SCHEMBL16902664 | 0.75 | HRH3 (0.50) | ALDH1A1 | |
| SCHEMBL11334612 | 0.75 | CHRNB4 (0.44) | CHRNB4CHRNA3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |