Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 14/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270942 | 1.00 | HTR3A (0.55) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL9443220 | 1.00 | HTR3A (0.55) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL7280117 | 0.99 | HTR3A (0.54) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL7280110 | 0.99 | HTR3A (0.54) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL7270924 | 0.98 | HTR3A (0.55) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL7270920 | 0.98 | HTR3A (0.55) | HTR3AKCNH2CYP3A4 | |
| SCHEMBL7270849 | 0.96 | HTR3A (0.51) | HTR3AKCNH2 | |
| SCHEMBL7269216 | 0.96 | HTR3A (0.51) | HTR3AKCNH2 | |
| SCHEMBL7270520 | 0.96 | HTR3A (0.51) | HTR3AKCNH2 | |
| SCHEMBL7276361 | 0.94 | HTR3A (0.51) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430190-B1 | New tricyclic compounds | SYNTEX INC (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5202333-A | Tricyclic 5-HT3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0430190-A2 | New tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-06-05 | — | — | EP | disclosed |