SCHEMBL7271

SCHEMBL7271

CCCCC(=O)O[C@H]1C[C@@]2(C)[C@@H](C[C@H](C)[C@]2(OC(=O)CC)C(=O)COC(=O)CC)[C@@H]2CCC3=CC(=O)C=C[C@]3(C)C12F

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 7/20 0.78
▸ PGR P06401 4/20 0.78
▸ MAPT P10636 3/20 0.78
▸ ADORA3 P0DMS8 2/20 0.78
▸ NR1I2 O75469 2/20 0.78
▸ DRD2 P14416 1/20 0.78
▸ OPRD1 P41143 1/20 0.78
▸ USP2 O75604 5/20 0.68
▸ CYP3A4 P08684 5/20 0.68
▸ MEN1 O00255 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ HIF1A Q16665 1/20 0.67
▸ AR P10275 1/20 0.67
▸ CHRM1 P11229 1/20 0.67
▸ CNR1 P21554 1/20 0.67
▸ TBXA2R P21731 1/20 0.67
▸ LMNA P02545 3/20 0.66
▸ SMN1; SMN2 Q16637 2/20 0.66
▸ NPSR1 Q6W5P4 2/20 0.66
▸ MLNR O43193 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20485505 1.00 NR3C1 (0.78) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL4174889 0.99 NR3C1 (0.77) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL11371970 0.97 NR3C1 (0.74) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL11749891 0.97 NR3C1 (0.76) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL1530974 0.96 NR3C1 (0.80) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL11748332 0.95 NR3C1 (0.84) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL29395436 0.95 NR3C1 (0.84) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL509817 0.95 NR3C1 (0.84) NR3C1PGRMAPTADORA3NR1I2
Propionic Acid SCHEMBL120209 0.94 NR3C1 (0.76) NR3C1PGRMAPTADORA3NR1I2
SCHEMBL6898103 0.94 NR3C1 (0.70) NR3C1PGRMAPTADORA3NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17445 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 — — US claimed
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 — — EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 — — EP claimed
EP-4724040-A1 TREATMENT OF PSORIASIS TRADOVA (PTY) LTD (ZA) 2026-04-15 — — EP claimed
EP-3820479-B1 METHODS TO REDUCE COMPLICATIONS OF INTRA-ARTICULAR STEROID TAIWAN LIPOSOME CO LTD (TW) 2026-03-11 — — EP claimed
EP-4680231-A1 USE OF ORAL JAK KINASE INHIBITORS TO TREAT LICHEN PLANUS Mayo Foundation for Medical Education and Research (US) 2026-01-21 — — EP claimed
US-12514820-B2 Pharmaceutical composition of intra-articular corticosteroid for pain control TAIWAN LIPOSOME CO., LTD. (TW) 2026-01-06 — — US claimed
EP-4301343-B1 PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME TLC BIOPHARMACEUTICALS INC (US) 2025-11-19 — — EP claimed
US-20250332120-A1 COMPOSITION FOR EXTERNAL PREPARATION KAO CORPORATION (JP) 2025-10-30 — — US claimed
US-20250319104-A1 MOISTURIZING CREAM FOR RADIATION DERMATITIS PERRY ARTHUR W (US) 2025-10-16 — — US claimed
EP-0068553-A1 Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 — — EP claimed
US-4343798-A Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-10 — — US claimed
US-4304765-A Ocular insert housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1981-12-08 — — US claimed
EP-0036138-A2 Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide MERCK & CO. INC. (US) 1981-09-23 — — EP claimed
US-4279900-A ANTIINFLAMMATORY INTREX RESEARCH CORPORATION (US) 1981-07-21 — — US claimed
US-4250164-A Method of treating psoriasis of the nails and composition BERNSTEIN JOEL E 1981-02-10 — — US claimed
US-4244942-A Creamy preparation containing steroid and process for the preparation thereof TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1981-01-13 — — US claimed
US-4230621-A TRACERS, HYDROXYPHENYLGLUTARIC ACID DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1980-10-28 — — US claimed
US-4083974-A Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether THE UPJOHN COMPANY (US) 1978-04-11 — — US claimed
US-4070462-A Steroid ointment SCHERING CORPORATION (US) 1978-01-24 — — US claimed
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