Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863169 | 1.00 | PTGS1 (0.47) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL10336122 | 0.88 | HIF1A (0.48) | PTGS1SLC7A5CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL11446574 | 0.86 | CYP3A4 (0.38) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL2778928 | 0.84 | ALPI (0.47) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL28232490 | 0.84 | CHRM1 (0.43) | PTGS1ALPIPKMXIAPSLC7A5 | |
| Merophan SCHEMBL31473334 | 0.83 | CYP1A2 (0.48) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL27339211 | 0.80 | CSNK1E (0.44) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL27339210 | 0.80 | CSNK1E (0.44) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL2781695 | 0.80 | ALPI (0.50) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL5069630 | 0.80 | ALPI (0.50) | PTGS1ALPIPKMXIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105627-B | Unnatural base pair compositions and methods of use | 斯克利普斯研究所 | 2024-07-02 | — | — | CN | disclosed |
| CN-118139868-A | Orally bioavailable nucleoside analogs | 维纳拓尔斯制药公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114126619-B | Compounds for the synthesis of peptidomimetics | 范因斯坦医学研究院 | 2024-03-15 | — | — | CN | disclosed |
| CN-111182880-B | WNT compositions and process from serum-free culture conditions | 安卡萨再生疗法公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116445398-A | WNT composition and purification method | 小利兰斯坦福大学托管委员会 | 2023-07-18 | — | — | CN | disclosed |
| CN-116457034-A | Nanomaterial and method of use thereof | 康涅狄格大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114853866-A | Peptidomimetic macrocycles | 艾瑞朗医疗公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114761026-A | Compositions and methods for in vivo synthesis of non-native polypeptides | 斯克利普斯研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-114746099-A | Eukaryotic semisynthetic organisms | 斯克利普斯研究所 | 2022-07-12 | — | — | CN | disclosed |
| CN-112500466-B | Peptidomimetic macrocycles | 艾瑞朗医疗公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-102762208-A | Pyrazolopyrimidines and related heterocycles as ck2 inhibitors | CYLENE PHARMACEUTICALS INC | 2012-10-31 | — | — | CN | disclosed |
| CN-102625807-A | 4-substituted pyridin-3-yl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2012-08-01 | — | — | CN | disclosed |
| CN-102573846-A | Heterocyclic compounds and their use | INTELLIKINE INC | 2012-07-11 | — | — | CN | disclosed |
| CN-100491339-C | Technique for synthesizing antineoplastic melphalan | SUZHOU LEADER CHEMICAL CO LTD (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-101100440-A | Technique for synthesizing antineoplastic melphalan | SUZHOU LEADER CHEMICAL CO LTD (CN) | 2008-01-09 | — | — | CN | disclosed |
| US-6582908-B2 | Nucleotide sequences for use as tool in genetic engineering | AFFYMETRIX, INC. | 2003-06-24 | — | — | US | disclosed |
| US-20010053519-A1 | Oligonucleotides | AFFYMETRIX, INC. | 2001-12-20 | — | — | US | disclosed |
| US-6022714-A | Methods for attachment of a polynucleotide to a preselected material | GENETICS INSTITUTE (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0380623-B1 | IRREVERSIBLE PEPTIDE LIGANDS FOR BOMBESIN RECEPTORS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-09-29 | — | — | EP | disclosed |
| US-5100873-A | Bombesin antagonist, anticancer agents, oligopeptides | FARMITALIA CARLO ERBA (IT) | 1992-03-31 | — | — | US | disclosed |