Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25141919 | 0.86 | CYP1A2 (0.52) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL16268136 | 0.85 | HIF1A (0.49) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL8950931 | 0.84 | CYP1A2 (0.50) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL7271045 | 0.83 | PTGS1 (0.47) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL8590724 | 0.83 | MEN1 (0.46) | TDP1MEN1KMT2AADAMTS5 | |
| SCHEMBL27863169 | 0.83 | PTGS1 (0.47) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL9225983 | 0.83 | CYP1A2 (0.48) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL9225980 | 0.83 | CYP1A2 (0.48) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL8398238 | 0.81 | CYP1A2 (0.47) | CYP1A2PTGS1ALPIPKMXIAP | |
| SCHEMBL8202673 | 0.80 | CYP1A2 (0.53) | CYP1A2PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854707-B | Cyclized berberine derivative and preparation method and application thereof | 石家庄学院 | 2025-05-16 | — | — | CN | disclosed |