Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | CLTC | Q00610 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271257 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1USP2 | |
| SCHEMBL7270170 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1USP2 | |
| SCHEMBL7279273 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1USP2 | |
| Hydrochloric Acid SCHEMBL7277534 | 0.99 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1USP2 | |
| Hydrochloric Acid SCHEMBL7278869 | 0.99 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1USP2 | |
| Hydrochloric Acid SCHEMBL7277541 | 0.99 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1USP2 | |
| SCHEMBL7271835 | 0.96 | HTR3A (0.42) | KDM4EALDH1A1HPGDMEN1USP2 | |
| SCHEMBL7271838 | 0.96 | HTR3A (0.42) | KDM4EALDH1A1HPGDMEN1USP2 | |
| SCHEMBL7278369 | 0.96 | HTR3A (0.42) | KDM4EALDH1A1HPGDMEN1USP2 | |
| Hydrochloric Acid SCHEMBL7279392 | 0.95 | HTR3A (0.41) | KDM4EALDH1A1HPGDMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457243-A1 | Novel tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | claimed |
| US-5202318-A | Antiserotonine, antiemetic agents | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0457243-A1 | Novel tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |