SCHEMBL7271330

SCHEMBL7271330

C[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1C(=O)N(Cc2ccccc2)C[C@H]1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACE P12821 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7271272 0.92 ACE (1.00) ACE
SCHEMBL7263641 0.92 ACE (1.00) ACE
SCHEMBL7263646 0.92 ACE (1.00) ACE
SCHEMBL7270448 0.91 ACE (1.00) ACE
SCHEMBL7265312 0.91 ACE (1.00) ACE
SCHEMBL7264384 0.90 ACE (1.00) ACE
SCHEMBL7272641 0.90 ACE (1.00) ACE
SCHEMBL7270378 0.90 ACE (1.00) ACE
SCHEMBL7270347 0.89 ACE (0.88) ACE
SCHEMBL7263606 0.89 ACE (0.88) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4508727-A Antihypertensive 2-oxo-imidazolidine derivatives TANABE SEIYAKU CO., LTD. (JP) 1985-04-02 US disclosed
EP-0095163-A2 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition Tanabe Seiyaku Co., Ltd. (JP) 1983-11-30 EP disclosed