Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011990 | 1.00 | ARG1 (0.58) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL26135483 | 1.00 | ARG1 (0.58) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL30571902 | 0.82 | ARG1 (0.40) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL5197240 | 0.81 | ARG1 (0.60) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL3675363 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL1512874 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL3675362 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL1512877 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL3676541 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 | |
| SCHEMBL4302105 | 0.81 | ARG1 (0.59) | ARG1CYP1A2ALOX15CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |