Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.57 |
| ▸ | NOS1 | P29475 | 4/20 | 0.57 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 2/20 | 0.37 |
| ▸ | ARG2 | P78540 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271597 | 1.00 | NOS2 (0.57) | NOS2NOS1NOS3GGT1ARG1 | |
| SCHEMBL14607055 | 0.82 | NOS2 (0.61) | NOS2NOS1NOS3GGT1ARG1 | |
| Hydrochloric Acid SCHEMBL27558018 | 0.80 | NOS2 (0.64) | NOS2NOS1NOS3GGT1ARG1 | |
| Hydrochloric Acid SCHEMBL5642573 | 0.80 | NOS2 (0.64) | NOS2NOS1NOS3GGT1ARG1 | |
| Hydrochloric Acid SCHEMBL5642844 | 0.80 | NOS2 (0.64) | NOS2NOS1NOS3GGT1ARG1 | |
| SCHEMBL5517028 | 0.77 | NOS2 (0.48) | NOS2NOS1NOS3GGT1ARG1 | |
| SCHEMBL440968 | 0.77 | NOS2 (0.48) | NOS2NOS1NOS3GGT1ARG1 | |
| SCHEMBL5518580 | 0.77 | NOS2 (0.48) | NOS2NOS1NOS3GGT1ARG1 | |
| Hydrochloric Acid SCHEMBL5642582 | 0.76 | NOS2 (0.51) | NOS2NOS1NOS3GGT1ARG1 | |
| SCHEMBL7271743 | 0.75 | NOS2 (0.49) | NOS2NOS1NOS3GGT1ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |