Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271665 | 1.00 | SLC2A1 (0.64) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| SCHEMBL515430 | 0.91 | SLC2A1 (0.74) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| Bromide SCHEMBL11515734 | 0.90 | SLC2A1 (0.72) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| SCHEMBL27849455 | 0.86 | SLC2A1 (0.85) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL7272231 | 0.84 | SLC2A1 (0.87) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL7282863 | 0.84 | SLC2A1 (0.70) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL10452455 | 0.84 | SLC2A1 (0.87) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| SCHEMBL7279400 | 0.84 | ALDH1A1 (0.72) | SLC2A1SIGMAR1ADRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13344551 | 0.84 | SLC2A1 (0.87) | SLC2A1SIGMAR1ADRB2DRD2DRD1 | |
| SCHEMBL7435099 | 0.83 | ATM (0.76) | SLC2A1SIGMAR1ADRB2POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4885313-A | 3,4-Dihydroxyphenylethylamine derivatives and their use | FISONS PLC (GB) | 1989-12-05 | — | — | US | disclosed |
| US-4803225-A | Dihydroxy-phenethylamino compounds useful as pharmaceuticals | FISONS, PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| US-4720586-A | Substituted 3,4-dihydroxy-phenylethylamino compounds | FISONS, PLC (GB) | 1988-01-19 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |