Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | TRHR | P34981 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271688 | 1.00 | CAPN1 (0.40) | CAPN1CTSBSLC6A2ELANETRHR | |
| SCHEMBL7273752 | 0.93 | ELANE (0.41) | ELANEMEN1KMT2AXIAP | |
| SCHEMBL7280679 | 0.89 | KMT2A (0.45) | ELANETRHRKMT2AXIAP | |
| SCHEMBL7280675 | 0.89 | KMT2A (0.45) | ELANETRHRKMT2AXIAP | |
| SCHEMBL7272196 | 0.84 | CAPN1 (0.43) | CAPN1CTSBTRHRMEN1KMT2A | |
| SCHEMBL7272470 | 0.84 | TRHR (0.42) | CAPN1TRHR | |
| SCHEMBL7273516 | 0.83 | TRHR (0.42) | TRHR | |
| SCHEMBL7273642 | 0.81 | TRHR (0.41) | TRHR | |
| SCHEMBL7273636 | 0.81 | ACE (0.42) | TRHR | |
| SCHEMBL7282397 | 0.80 | CAPN1 (0.41) | CAPN1CTSBSLC6A2ELANETRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |