Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935989 | 1.00 | GRM1 (0.44) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL24520293 | 1.00 | GRM1 (0.44) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL935518 | 0.98 | GRM1 (0.46) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL25661095 | 0.94 | GRM1 (0.46) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL935831 | 0.94 | GRM1 (0.46) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL24520216 | 0.78 | GRM1 (0.43) | GRM1GRIK1DPP7GRIK2PTGS1 | |
| SCHEMBL24548562 | 0.78 | GRM1 (0.43) | GRM1GRIK1DPP7GRIK2PTGS1 | |
| SCHEMBL936219 | 0.78 | GRM1 (0.43) | GRM1GRIK1DPP7GRIK2GRIA1 | |
| SCHEMBL24548640 | 0.78 | GRM1 (0.43) | GRM1GRIK1DPP7GRIK2PTGS1 | |
| SCHEMBL5103968 | 0.76 | ALDH1A1 (0.55) | GRM1GRIK1DPP7PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015529-A1 | G PROTEIN PEPTIDOMIMETICS | Vrije Universiteit Brussel (BE) | 2022-06-22 | — | — | EP | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |