Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7285673 | 0.91 | ITGB3 (0.43) | ITGB3ITGA2BFFAR4PRSS1F2 | |
| Water SCHEMBL8881880 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BPPARDFFAR1PPARG | |
| SCHEMBL7275930 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7272750 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Water SCHEMBL8881986 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7275215 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1F2ST14 | |
| SCHEMBL7283093 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7276387 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7273468 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7275114 | 0.84 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |