Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.68 |
| ▸ | CCND1 | P24385 | 3/20 | 0.68 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.68 |
| ▸ | CDK1 | P06493 | 2/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.68 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272006 | 1.00 | CDK4 (0.68) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL4622274 | 0.91 | HDAC8 (0.68) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL4622268 | 0.91 | HDAC8 (0.68) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL2573994 | 0.86 | TUBB1 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL6036139 | 0.83 | HDAC8 (0.65) | HDAC8KDM4EPTGER1PTGER4PTGER3 | |
| SCHEMBL6036142 | 0.83 | HDAC8 (0.65) | HDAC8KDM4EPTGER1PTGER4PTGER3 | |
| SCHEMBL7228421 | 0.83 | CCNB2 (0.61) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7228424 | 0.83 | CCNB2 (0.61) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL3906735 | 0.81 | CDK4 (1.00) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7272039 | 0.81 | CDK4 (1.00) | CDK4CCND1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181090-C | Aspartyl dipeptide ester derivatives and sweeteners | ֮����ʽ���� | 2004-12-22 | — | — | CN | disclosed |
| US-6548096-B1 | Aspartyl dipeptide ester derivatives and sweeteners | AJINOMOTO CO., INC. (JP) | 2003-04-15 | — | — | US | disclosed |
| CN-1296493-A | Aspartyl dipeptide ester derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-05-23 | — | — | CN | disclosed |
| EP-1070726-A1 | ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-01-24 | — | — | EP | disclosed |