Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 5/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302678 | 1.00 | SLC1A1 (0.47) | SLC1A1SLC1A3SLC1A2GLO1USP2 | |
| SCHEMBL9129749 | 0.83 | TDP1 (0.41) | SLC1A1SLC1A3SLC1A2GSRGRM8 | |
| SCHEMBL7271506 | 0.82 | GSR (0.50) | SLC1A1SLC1A3SLC1A2GLO1GSR | |
| SCHEMBL5280980 | 0.82 | GSR (0.50) | SLC1A1SLC1A3SLC1A2GLO1GSR | |
| SCHEMBL7864753 | 0.80 | SLC1A2 (0.50) | SLC1A1SLC1A3SLC1A2GLO1GRIK1 | |
| SCHEMBL29126191 | 0.80 | SLC1A2 (0.50) | SLC1A1SLC1A3SLC1A2GLO1GRIK1 | |
| SCHEMBL8746986 | 0.77 | USP2 (0.48) | SLC1A1SLC1A3SLC1A2USP2SLCO1B1 | |
| SCHEMBL9725300 | 0.75 | USP2 (0.50) | SLC1A1SLC1A3SLC1A2GLO1USP2 | |
| SCHEMBL8694838 | 0.74 | CHRM1 (0.48) | SLC1A1SLC1A3SLC1A2GLO1GRIK1 | |
| SCHEMBL27121895 | 0.74 | CYP1A2 (0.56) | SLC1A1SLC1A3SLC1A2GSRGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |