Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280980 | 1.00 | GSR (0.50) | GSRCPB2RNPEPSLC1A1SLC1A3 | |
| SCHEMBL28011992 | 0.85 | GSR (0.45) | GSRCPB2RNPEPSLC1A1SLC1A3 | |
| SCHEMBL482963 | 0.82 | CPB2 (0.44) | GSRCPB2RNPEPSLC1A1SLC1A3 | |
| SCHEMBL482961 | 0.82 | CPB2 (0.44) | GSRCPB2RNPEPSLC1A1SLC1A3 | |
| SCHEMBL7272045 | 0.82 | SLC1A1 (0.47) | GSRSLC1A1SLC1A3SLC1A2GLO1 | |
| SCHEMBL5302678 | 0.82 | SLC1A1 (0.47) | GSRSLC1A1SLC1A3SLC1A2GLO1 | |
| SCHEMBL7864753 | 0.80 | SLC1A2 (0.50) | SLC1A1SLC1A3SLC1A2GLO1SLC7A5 | |
| SCHEMBL29126191 | 0.80 | SLC1A2 (0.50) | SLC1A1SLC1A3SLC1A2GLO1SLC7A5 | |
| SCHEMBL20915027 | 0.79 | GSR (0.44) | GSRCPB2RNPEPSLC1A1SLC1A3 | |
| SCHEMBL20915026 | 0.79 | GSR (0.44) | GSRCPB2RNPEPSLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |