Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.91 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.73 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RARA | P10276 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31603897 | 1.00 | RARB (0.91) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10358713 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10782387 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL4174175 | 0.95 | RARB (1.00) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10785291 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10357796 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9483141 | 0.95 | RARB (1.00) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10781475 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7836467 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7838644 | 0.95 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1638-H | CYCLIC HEXAPEPTIDE | FURUTA TAKAHISA (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0462531-B1 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0729974-A1 | Cyclic polypeptide with antibiotic activity and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5376634-A | Microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4707296-A | LIQUID CRYSTALS, OPTICAL APPARATUS | CHISSO CORPORATION (JP) | 1987-11-17 | — | — | US | disclosed |