Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.68 |
| ▸ | RARA | P10276 | 1/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483141 | 1.00 | RARB (1.00) | RARBTP53TSHRPLA2G4BRARA | |
| SCHEMBL10358386 | 0.96 | RARB (0.92) | RARBTP53TSHRPLA2G4BRARA | |
| SCHEMBL7272084 | 0.95 | RARB (0.91) | RARBTP53TSHRPLA2G4BRARA | |
| SCHEMBL31603897 | 0.95 | RARB (0.91) | RARBTP53TSHRPLA2G4BRARA | |
| SCHEMBL7336812 | 0.92 | RARB (0.90) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8081583 | 0.92 | RARB (0.90) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7836467 | 0.91 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10781475 | 0.91 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7838644 | 0.91 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10358713 | 0.91 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220296579-A1 | COMPOSITIONS AND METHODS FOR PROVIDING CARDIOPROTECTIVE EFFECTS | CORNELL UNIVERSITY (US) | 2022-09-22 | — | — | US | disclosed |
| US-11191755-B2 | Compositions and methods for providing cardioprotective effects | CORNELL UNIVERSITY (US) | 2021-12-07 | — | — | US | disclosed |
| US-11160769-B2 | Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists | CORNELL UNIVERSITY (US) | 2021-11-02 | — | — | US | disclosed |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1907347-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | Arcadia Pharmaceuticals Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296579-A1 | COMPOSITIONS AND METHODS FOR PROVIDING CARDIOPROTECTIVE EFFECTS | RARB, RARG, RARA | RARB 1/4885TP53 3965/4885TSHR 594/4885 |
| US-11191755-B2 | Compositions and methods for providing cardioprotective effects | RARB, RARG, RARA | RARB 1/4885TP53 3965/4885TSHR 594/4885 |
| US-11160769-B2 | Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists | RARA, RARG, RXRA | RARB 5/4885TP53 3142/4885TSHR 113/4885 |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | RARB, RARA, RARG | RARB 1/4885TP53 836/4885TSHR 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.