Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.59 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272184 | 1.00 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3439635 | 0.91 | HDAC3 (0.69) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3439636 | 0.91 | HDAC3 (0.69) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Malonic Acid SCHEMBL8631198 | 0.81 | HDAC1 (0.51) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL417723 | 0.81 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL5517018 | 0.80 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL11035994 | 0.80 | ALDH1A1 (0.51) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Bicarbonate SCHEMBL17180457 | 0.80 | MAOB (0.58) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Bicarbonate SCHEMBL980228 | 0.79 | MAOB (0.56) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL12148878 | 0.79 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116963724-A | Treatment for human malignant pleural effusion | 萨恩帕斯药物有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116963724-A | Treatment for human malignant pleural effusion | 萨恩帕斯药物有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116710123-A | Cytokine release and inhibition of cytokine storm | 萨恩帕斯药物有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-112272555-A | Dosing regimens for treating proliferative disorders | 萨恩帕斯药物有限公司 | 2021-01-26 | — | — | CN | disclosed |
| US-7906643-B2 | Methylene blue-curcumin analog for the treatment of Alzheimer's Disease | CODMAN & SHURTLEFF, INC. (US) | 2011-03-15 | — | — | US | disclosed |