Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272366 | 0.99 | CHRNA7 (0.56) | HTR3ACHRNA7GAAATMLSS | |
| Hydrochloric Acid SCHEMBL7271486 | 0.78 | CHRNA7 (0.52) | HTR3ACHRNA7 | |
| SCHEMBL7281942 | 0.77 | HTR3A (0.58) | HTR3ACHRNA7LSS | |
| SCHEMBL7280683 | 0.77 | HTR3A (0.58) | HTR3ACHRNA7LSS | |
| SCHEMBL7280641 | 0.76 | CHRNA7 (0.44) | HTR3ACHRNA7 | |
| Hydrochloric Acid SCHEMBL7279926 | 0.76 | HTR3A (0.57) | HTR3ACHRNA7LSS | |
| Hydrochloric Acid SCHEMBL7272905 | 0.76 | HTR3A (0.57) | HTR3ACHRNA7LSS | |
| SCHEMBL9469749 | 0.75 | GAA (0.50) | CHRNA7GAAATMLSS | |
| Hydrochloric Acid SCHEMBL7272294 | 0.75 | CHRNA7 (0.43) | HTR3ACHRNA7 | |
| SCHEMBL7270883 | 0.74 | CHRM1 (0.44) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643923-A | TREATMENT OF ANXIETY, COGNITION ACTIVATORS, SENILITY OR ALZHEIMER'S | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0456519-B1 | Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-07-13 | — | — | EP | disclosed |
| EP-0456519-A1 | Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1991-11-13 | — | — | EP | disclosed |