Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7281668 | 0.91 | ITGB3 (0.38) | ITGB3ITGA2BOPRM1OPRD1OPRK1 | |
| SCHEMBL7276523 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BCHRM4OPRM1OPRD1 | |
| SCHEMBL7274101 | 0.87 | ITGB3 (0.41) | ITGB3ITGA2BCHRM4OPRM1OPRD1 | |
| SCHEMBL7277017 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BCHRM4OPRM1OPRD1 | |
| Water SCHEMBL7281582 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BCHRM4OPRM1OPRD1 | |
| SCHEMBL7277096 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BCHRM4ITGAVNAMPT | |
| SCHEMBL7277328 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BCHRM4ITGAVNAMPT | |
| SCHEMBL7275524 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BCHRM4OPRM1OPRD1 | |
| SCHEMBL7274663 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BOPRM1OPRD1ITGAV | |
| SCHEMBL7275380 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BCHRM4ITGAVDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |