Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272010 | 0.89 | TRHR (0.47) | TRHR | |
| SCHEMBL7271847 | 0.87 | TRHR (0.48) | TRHR | |
| SCHEMBL7271921 | 0.84 | TRHR (0.46) | TRHR | |
| SCHEMBL7271810 | 0.84 | EPHA2 (0.38) | TRHREPHA2 | |
| SCHEMBL7271930 | 0.83 | TRHR (0.46) | TRHR | |
| SCHEMBL7273390 | 0.83 | TRHR (0.43) | TRHREPHA2 | |
| SCHEMBL12228297 | 0.80 | TRHR (0.49) | TRHR | |
| SCHEMBL7273256 | 0.79 | TRHR (0.54) | TRHR | |
| SCHEMBL7278785 | 0.78 | EPHA2 (0.39) | TRHREPHA2 | |
| SCHEMBL7278770 | 0.78 | EPHA2 (0.39) | TRHREPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |